Showing posts with label spina bifida. Show all posts
Showing posts with label spina bifida. Show all posts

Wednesday, October 7, 2015

DNA Methylation and Neural Tube Defects: A Closer Look at Spina Bifida

Did you know that neural tube defects are among the most common form of human birth defects? These defects result in the abnormal development of the brain, spine, or spinal cord. Often, this occurs within the first month of pregnancy, and the reasons behind these disorders are unclear. There are about 8 babies born in the U.S. each day that are affected and 300,000 cases identified each year. Among neural tube defects, spina bifida is one of the most common. Spina bifida occurs when the neural tube does not close properly during fetal development (image 1). This can then leave a bulge in the skin in the area that is affected, or in severe cases, the skin could be open with the nerves exposed.